The June 19 edition of Science News contains an article entitled The Science and ART of Human Reproduction as part of their Century of Science series reporting the impact on society of major scientific advances of the last 100 years.
In my book, and in abbreviated versions under tabs on this site, I discuss how people began to think about the origin of life from antiquity. Philosophers debated issues of when a growing fetus became a human being, the timing of ensoulment, and the morality of abortion and neonaticide. In this Science News article, the authors point out that, until the 17th century, the prevailing theories were that minuscule humans already existed fully formed either in the mother’s menstrual blood or in the father’s semen. There was no belief, unlike the common assertion today, that the “thing” in the mother’s body is a “piece of tissue” to be discarded for convenience.
In any case, fertility was never a sure thing, and even today about 15% of couples worldwide are not able to conceive naturally. Many of us understand how sorrowful this can be. The advent of in vitro fertilization changed everything. Variations on this technique are now known as assisted reproductive technology (ART). Some 9 million babies have already been born this way, and tens of millions of embryos are frozen and waiting their turn to become babies. This article recognizes that all of these embryos are human beings whether implanted to grow into a baby or frozen for future use.
The impact of ART on society has been huge since infertile couples can now have children, as can same-sex couples and single adults. Sometimes this involves a surrogate mother to bear the child to delivery. ART is currently used roughly 3 times more often in Europe than in the United States.
Sometimes women or men who need to be treated for cancer will donate eggs or sperm to be frozen and used later. Sometimes men and women headed into combat donate sperm or eggs to be frozen and used in case they do not return. In other cases, women freeze their eggs to be used at another date when it is a better time in life to have a baby, perhaps when she is older and she has a more favorable life-style situation. This has become known as “social freezing.” In one study, only 6.5% of women ever returned to use their frozen eggs or embryos.
The article goes on to explain that technological innovations now permit the doctor to inject a single sperm into an egg to produce fertilization. In the seminal study, this was done to 47 eggs, 15 cells grew to embryos to be implanted, and 4 live births ultimately occurred. This method is now used in roughly two-thirds of ART cycles and thus has largely replaced IVF. There is still a lot of wasted life.
Pre-implantation genetic diagnosis (PGD) involves sampling the growing embryo to check such things as sex and markers for genetic diseases. This is now common, and doctors may use the findings to decide to implant the egg or not. Many state laws have been passed to forbid abortion of a pregnancy on the basis of sex selection and for a diagnosis of Down Syndrome, and sometimes for other circumstances. Most of these have been struck down by federal courts, but a case involving a MIssissippi law soon will be heard by the Supreme Court, and pro-life supporters hope the court will rule that the individual states have the right to regulate such matters.
In the meantime, there is open discussion of using the gene-editing CRISPR technology in the future to perform certain changes to the embryo such as for disease prevention or to design certain other characteristics into the developing child. Identifying which regions of the genome are responsible for developing into various characteristics has its origin in 1924. Breakthroughs occurred in 1965 and again in 1995. Ultimately, society will need to address the issue of designer babies. In China, a doctor has already (illegally) manipulated the genome of two children who were born healthy.
While being sympathetic to the circumstances many people experience in wanting a child, we meet the concurrent waste of human life which is inherent to the success from bringing a child to birth. It makes many feel ambivalent and uncomfortable. The issues of how to use PGD and how to regulate designer babies also must be faced.
The purposes of this blog is to provide the reader with information and education on complicated issues concerning human life and dignity. I trust the reader to use the information wisely when it is time to shape the future of our society.